A Comprehensive Survey on Super-Resolution Techniques in Medical Imaging
December 15, 2025
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Corresponding Author: Nirvana Mansour, Independent Researcher, Endodontic Lecturer, Private Clinic, Egypt
The use of platelet concentrates in dentistry evolves frequently, from the initial platelet-rich plasma (PRP) to sophisticated centrifugation procedures and injectable PRF preparations. Alveolar ridge augmentation, periodontal surgery, implant surgery, and endodontic regeneration are just a few of the disciplines that have used platelet concentrates for hard and soft tissue healing.
With breakthroughs in surgical approaches, some authors have proposed the combination of platelet concentrates with bone graft materials such as synthetic bone, xenografts and allografts, a novel idea that involves creating “sticky bone,” a growth factor-enriched bone graft matrix. This composite biomaterial, is a promising autologous material, results in a significant release of cytokines and autologous growth factors that responsible for healing and tissue recovery, in addition, these growth factors promote proliferation of mesenchymal stem cells, fibroblasts, and osteoblasts, impacting the development of tissue neoformation.
Sticky bone application in regenerative endodontic surgery in cases of through and through lesions, apico-marginal defects, and non-healed large apical lesions after root canal treatment will modulate the microenvironment in periapical defects that demand guided tissue regeneration (GTR), which combines the use of bone graft material plus a resorbable or non-resorbable membrane, and this may elicit some immunological response. So, using sticky bone after apicoectomy provides us with an autologous growth factor-enriched bone graft matrix that simplifies handling during the surgical operations due to its optimal moldability without disintegration into the surrounding soft tissues. It also allows stabilization of the bone graft in the defect to accelerate tissue healing with the elimination of graft loss and inhibits the ingrowth of soft tissue in the graft, which results in complementing the surgery and increasing the success rate.
